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Maternal and fetal outcomes in pregnancies complicated by overweight and obesity

The medication is metabolized by proteolytic cleavage and beta-oxidation, with metabolites eliminated via urine and feces

Metformin, a drug widely used in the treatment of diabetes, has been found to exert its antidiabetic effects by changing the gut microbiota, partially restoring the gut dysbiosis associated with T2DM 184

No current-medication review

Among patients with available renal function data ( n = 4), estimated glomerular filtration rate (eGFR) values ranged from 15 to 59 mL/min/1.73 m, indicating varying degrees of potential renal impairment

Elmquist JK, Dulac C, editors