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Immune homeostasis dysregulation and autoimmunity risk: as CUL5 is a key negative feedback regulator of both T-cell receptor (TCR) and cytokine signaling pathways (21), its excessive inhibition may lead to hyperactivation of T-cell signaling, breaking immune tolerance and increasing the risk of attacking normal tissues, thereby potentially triggering autoimmune diseases or severe inflammatory responses
Laser Doppler Perfusion Imaging was used to detect the blood flow perfusion
Syed is recognized as a leading voice in obesity medicine throughout the Rochester community
MetaboAnalyst 2.0a comprehensive server for metabolomic data analysis
- Phase 2: Focuses on the drug's effectiveness and further evaluates its safety in a larger group of individuals with the targeted condition