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Fer-1 alleviates abnormal expressions of tsRNA, with tsRNA-3029b being an effective target, and inhibiting tsRNA-3029b can inhibit ferroptosis and promote neuronal regeneration

3 In mammalian species, the dimeric cytosolic GSTs are abundantly expressed in many tissues and grouped into seven distinct isoenzyme classes termed alpha, pi, mu, omega, sigma, theta and zeta

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Common clinical drivers include: Vitamin B12 deficiency Folate deficiency Chronic liver disease Alcohol use disorder Medications (e.g., methotrexate) Bone marrow disorders Chronic inflammatory disease Hypothyroidism Key ICD-10 principle: Cell size is a laboratory observation