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10.1161/CIR.0000000000000757 10

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The main issue noted in studies is a short-term worsening of diabetic retinopathy in patients with severe pre-existing disease when blood sugar levels improve quickly

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In the realm of creating targeted DDSs, there are three prominent synthetic methods for producing polymerdrug conjugates: binding therapeutic compounds to synthetic polymeric carriers, incorporating therapeutic molecules with monomers prior to the polymerization process, and embedding drugs into polymers during their formation [62]