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Medically reviewed by FormBlends Medical Team Updated: March 2026 Disclosure: FormBlends is one of the providers compared in this article

doi: 10.1016/j.diabet.2012.08.011 10 ChenGTanCLiuXWangXTanQChenY

However, when you lose weight quickly, as is more often the case with GLP-1 medications, the risk of muscle loss increases

Regarding the GLP-1/GIP/glucagon tri-agonist molecule retatrutide, the TRIUMPH-Outcomes program (54) will assess kidney outcomes as a co-primary endpoint, while mechanistic insights are expected from the J1I-MC-GZBU study, in which the effects of retatrutide on mGFR and kidney physiology by multiparametric kidney MRI are investigated

Semaglutide is a medication used primarily for type 2 diabetes management and weight loss

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