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This approach is best suited for women with clear clinical indications, such as low libido, reduced strength, or significant lean mass loss

Discussion The efficacy of conventional chemotherapeutic agents is often limited by the robust antioxidant defense mechanisms inherent in cancer cells, which help neutralize the reactive oxygen species (ROS) generated during chemotherapy

Its medical use is experimental or off-label

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These include IGF-1R antagonists (e.g., linsitinib, teprotumumab) to suppress pathogenic IGF-1 signaling, IGFBP-4 or IGFBP-5 inhibitors to limit pro-fibrotic effects, and IGF mimetics or IGFBP-3 derivatives to restore protective IGF signaling in endothelial cells (Torr et al., 2023

Cognitive Performance: Supports mental clarity and focus, enhancing overall cognitive function