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In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

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Other animal models of FM include the chronic constriction injury model, which involves the compression of a nerve to induce neuropathic pain 37 , and the ovariectomy model, which involves the removal of the ovaries to induce hormonal changes that may be associated with FM 37

The company posted EPS of 71 cents, which met consensus estimates