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Efficiency of CREM knockdown by siRNA (n = 3) or CREM over-expression (n = 4) in HL-60 cells validated by qPCR ( c ) and western blot ( d )

185 Interestingly, intravenous injection of EVs from young mice stimulated PGC-1 expression through their miRNA cargo, thereby improving mitochondrial function and prolonging the lifespan of aged mice

Although Carbajal was only on the medication for a short period of time, he saw the progress and had no side effects

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