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For example, the FTO rs9939609 variant affects hunger signals and metabolic ratepatients with specific FTO profiles may experience faster appetite reduction but need stronger medication response to see weight loss, or vice versa
Acute illness, severe vomiting, or signs of dehydration
Genetic Factors and Personalized GLP-1 Response Emerging research suggests genetic variation in GLP-1 receptor pathways, GIPR signaling, and metabolic genes may influence individual GLP-1 response patterns
Older patients (60+) with arteriosclerosis have a possibility of circulatory collapse after administration
Food Chem Toxicol 62:869875 Wen X, Huang A, Hu J, Zhong Z, Liu Y, Li Z, Pan X, Liu Z (2015) Neuroprotective effect of astaxanthin against glutamate-induced cytotoxicity in HT22 cells: involvement of the Akt/GSK-3 pathway