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Patients should be aware that heavy, chronic ethanol use may counteract the therapeutic effects of vitamin B12

In contrast, the no loading dose regimen resulted in a gradual increase, reaching a median vitamin B12 concentration of 717 pmol/L after 90 days

Many patients notice significant improvements in their energy and overall well-being after starting treatment

But dogs with digestive disorders or other health issues may not be able to absorb enough of it, and the resulting B12 deficiency can cause serious health problems, including diarrhea, weight loss, and even seizures

Vitamin B-12 is used primarily in large animals