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The role of SIRT3 in homeostasis and cellular health

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The effects of NAC or L-NAC against PQ-induced cytotoxicity in A549 cells were assessed by measuring cellular PQ uptake, intracellular glutathione content, ROS levels, mitochondrial membrane potential, cellular gene expression, inflammatory cytokine release and cell viability

Most protocols recommend 2-4 weeks at initial doses assessing tolerance and early response indicators

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