In 2025, the European Medicines Agency concluded that NAION should be listed as a very rare side effect of semaglutide medications, including Ozempic, Wegovy, and Rybelsus, after reviewing clinical studies, adverse event reports, and post-market safety data
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Recovery times vary, but improvement generally begins within a few weeks and continues for several months as tissues regenerate
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Clinical trial data from semaglutide studies involving thousands of participants showed no increased thyroid cancer incidence in non-MTC populations
Both activate the same GLP-1 receptors and produce comparable metabolic effects
