17 in The New England Journal of Medicine
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline
Same patients, same clinics, same duration, random assignment
The problem is that lean mass alone cannot answer the clinical question we actually care about : Is the patient becoming weaker, less functional, poorly nourished, dehydrated, or less physically capable
"The most notable benefits of GLP-1 receptor agonists for patients with diabetes or obesity are their ability to promote significant weight loss, reduction in appetite, and improvement in blood sugar control," says Dr
Sema is engineered to facilitate advanced studies into GLP-1 receptor signaling, often researched for its potential impact on systemic recovery and metabolic biology