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(ii) CH is a positively charged polymer because of its amino groups, whereas GO has negatively charged carboxyl groups (-COOH)

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Device therapies such as intragastric balloon, endoscopic sleeve gastroplasty or vagal nerve blockade are generally less effective weight loss strategies than surgical intervention, but provide 1424% excess weight loss when used in the treatment of obesity [23]

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Frequency depends on your goals and the protocol