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Researchers are calling for larger studies that include: MRI imaging to document tissue healing Longer follow-up periods Comparison with traditional treatments Assessment of functional improvements beyond pain relief Standardized dosing and administration protocols As functional medicine practitioners continue to explore peptide therapys potential, we may see broader acceptance and integration of these treatments into mainstream medical practice

The paper does not report systemic toxicity panels, liver enzymes, or serum copper metrics

Provider involvement after approval is limited and hard to pin down

PLoS One (2012) 7(6):e38744

Endocrine 46 , 445454 (2014)

The researchers have shared their findings in a preprint research article on bioRxiv that is currently under peer review