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638 Saikosaponin B2 alleviates ER stress by regulating intracellular Ca 2+ levels, reducing lipid peroxidation and intracellular Fe 2+ content, and inhibiting ferroptosis in a GPX4-dependent manner, thereby improving CUMS-induced depressive behavior

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Inside the mitochondrial matrix, the acyl group is transferred back to CoA by carnitine palmitoyltransferase II (CPT-II), allowing the fatty acid to enter the -oxidation cycle