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J Biol Chem 285:3087530883 Huster D, Purnat TD, Burkhead JL, Ralle M, Fiehn O, Stuckert F et al (2007) High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease

This epigenetic mechanism is consistent with the broader Khavinson framework for bioregulator peptides, which proposes that short peptide sequences (27 amino acids) can penetrate nuclear membranes and interact directly with DNA or chromatin-associated proteins to modulate tissue-specific gene expression

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Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through Inhibition of ERK1/2 and Cyclin D1

Life Sciences 51(13):1049-1056. [doi.org]

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