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Extended escalation for sensitive individuals If standard 4-week intervals produce intolerable side effects, extending each phase to 6 or 8 weeks is a reasonable modification

Hmg-coa reductase inhibitors induce apoptosis of lymphoma cells by promoting ros generation and regulating akt, erk and p38 signals via suppression of mevalonate pathway

A pooled analysis of clinical trials showed a slightly elevated but not statistically significant risk

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