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Cytochrome P450 2E1 catalyzes the conversion of APAP to a toxic metabolite, N-acetyl-p-benzoquinone imine

The absorbance readings from test tubes reflect contributions from both unreacted H 2 O 2 (the desired signal) and various interfering substances present in biological samples

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Scale production Like other drugs, the production of NADs involves multiple technical stages, including raw material collection, synthesis, separation, purification, transportation, and storage, requiring large-scale production capabilities and stringent quality control

In details, serum separated, aliquoted and stored at -80 C within 1 h of venipuncture

Consider established treatments before experimental combinations