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Notably, in this experimental model, the lower atherosclerosis in G6PD-deficient mice cannot be attributed to the reduced bioavailability of NO since apoE / eNOS double knock-out mice show increased atherosclerosis [68]

Funding This work was supported by the Henan Provincial Breast Cancer Precision Prevention and Control Engineering Research Center (ZC20220050), the Henan Provincial Peoples Hospital23456 Talent Engineering Project (ZC23456026) and the study on the Effect and Mechanism of Macrophage-Derived Exosomes Loaded with Doxorubicin for Targeted Therapy of Triple-Negative Breast Cancer (ZC20220114)

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Treatment benefit is maximal at 16 mg/day as monotherapy [22]

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For more details, refer to Mayo Clinic Glutathione Information