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However, the impact of this improved bioenergetic and anti-inflammatory profile in PBMC, driven by NR, on MASLD was not explored, as these studies were not focused on MASLD, and liver function was assessed only through routine laboratory tests as part of the safety protocols, with no significant changes reported [99, 104]

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Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity