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The same large randomized clinical trials that showed positive cardiovascular results in subjects with type 2 diabetes also reported retinopathy complications as secondary outcomes

Both semaglutide and tirzepatide are FDA-approved GLP-1 based medications used to support weight management, but they differ significantly in their mechanism of action and clinical characteristics

A., Wharton, S., Yokote, K., Zeuthen, N., & Kushner, R

The article attributes specific early weight-loss numbers and a response percentage to a large semaglutide trial, but that trial titrated participants upward rather than holding them at the lowest step, so a step-specific figure is not something the article supports

World J Gastroenterol 24:45484553

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