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its a complex challenge impacted by hormones, metabolism, and health factors beyond our control

Progress tends to continue throughout the first year of treatment

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Specifically: Monitor routinely muscle strength and function amino-acid profiles short half-life proteins emerging resilience markers (e.g., GDF-15) Mitigate proactively adequate protein intake (1.21.5 g/kg/day) resistance or mixed exercise consider adjuncts that preserve muscle mass identify early biomarker patterns of ERM These steps do not contradict the use of GLP-1RAsthey optimize it

10.1186/s13023-021-01872-8 11 BattelliM