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Several physiological and clinical factors can influence the elimination rate of semaglutide, though the medication's pharmacokinetics are generally consistent across most patient populations

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A retrospective study on 650 ALS patients and 365 matched healthy controls revealed that 65% of ALS patients have dyslipidemia, mainly hypercholesterolemia, that is correlated with disease severity (Chestowska et al., 2021)

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