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10.1093/ajcn/nqab150 58

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Medications such as antidepressants and antipsychotics should be used only under the guidance of a qualified healthcare provider

Patients who implement calorie reduction and increase their activity levels typically experience faster and more pronounced benefits than those relying on medication alone

Large prospective longitudinal studies, including clinical trials, are needed to comprehensively explore the regulatory impact of leptin on bone and its potential implications for fracture risk (110, Table 1)