In total, six Novo Nordisk products including older diabetes medications Saxenda, Victoza, and Xultophy were reported to potentially be linked with these unusual side effects
Limited body composition data suggest that the majority of weight lost with tirzepatide is from fat mass, with a smaller proportion from lean mass, which is consistent with the pattern seen in other weight-loss interventions
The fundamentals matter regardless of medication: Calorie deficit through proper nutrition High protein intake (0.7-1g per pound daily minimum) Resistance training 2-4x weekly Adequate sleep and stress management Sustainable lifestyle changes Medications like retatrutide can be powerful tools, but they work best when combined with the basics
People working on maintaining weight loss after tirzepatide should keep nutrition high even as the weight stabilizes
Provide balanced information about risks and benefits
Babalghith AO, Al-kuraishy HM, Al-Gareeb AI, De Waard M, Sabatier JM et al (2022a) The Potential Role of Growth Differentiation Factor 15 in COVID-19: A Corollary Subjective Effect or Not
