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And retatrutide , a triple agonist targeting GLP-1, GIP, and glucagon receptors, has shown even greater weight loss than tirzepatide in early trials

Ozempic (Semaglutide) Ozempic, a brand name for Semaglutide injections, has been widely recognised for its effectiveness in glucose management in adults with type 2 diabetes (3)

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If tiredness is still severe after eight weeks at a stable dose, it's worth speaking to your SheMed clinician persistent fatigue at that stage is less likely to be purely medication-related and may have another cause worth investigating