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However, immunotherapy has exhibited limited efficacy in CRC primarily due to the reduced neoantigen burden of tumor cells, which hampers CD8+ T-cell activation and expansion as well as immunosuppressive factors present within the tumor microenvironment (48,49)
Hargrove DM, et al
CrossRef Gadoxetate-enhanced MRI Transitional Phase Parenchymal Signal: Effect on Washout and LI-RADS Diagnostic Performance for Hepatocellular Carcinoma Seong Hyeon Cho, Yong Jun Jung, Seung Baek Hong, Se Jin Choi, Seung Soo Lee, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin, Subin Heo, Sang Hyun Choi Radiology .2026;[Epub] CrossRef Hepatocellular carcinoma: current aspects of multidisciplinary management
2015;13:Doc14
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