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3b) while 2,6-dimethylcurcumin ( 11 ) and 4,4-dimethylcurcumin ( 12 ) activated the transcription to levels similar to those as curcumin, and compound 9 (acetalcurcumin) marginally but significantly activated SRE-mediated transcription

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It activates telomerase, the enzyme that maintains telomere length

And that is to compare, to look at whats the effect in the brain of GLP-1 and ketogenic diet to see if that in the brain, some of the effect is overlapping

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