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These pancreatic effects are complemented by improved peripheral insulin responsiveness in muscle tissue and lipid storage sites, facilitating glucose disposal and reducing systemic insulin resistance - a key driver of hepatic lipid accumulation and MASH progression [28,31]

Development of an ultra-performance liquid chromatography-electrospray ionization-Orbitrap mass spectrometry method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study

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Nat Clin Pract Endocrinol Metab 2:395407 Savage MO, Underwood L, Yordam N, Yuksel B, Smith A, Attie K, Camacho Hubner C (2006b) Treatment of short stature in children with severe primary IGF-I deficiency with once daily rhIGF-I/rhIGFBP-3 administration [abstract CF1-100]