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The correct dose, dose escalation schedule and safety monitoring requirements may change if retatrutide is approved in the future

Participants taking semaglutide lost an average of 15.2% of their initial body weight, while those on the placebo only lost 2.6%

Headaches Stuffy or runny nose Hives or a skin rash Nausea and gastrointestinal symptoms, including diarrhea or vomiting Asthma Anaphylaxis (though this is uncommon) These symptoms may appear after you eat foods with wheat, including bread, cereal, or granola