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In addition to altering food satiety signals, GLP-1 is suggested to modulate satiety in drugs of abuse and alter reward-related changes in multiple drugs of abuse such as cocaine (Hernandez et al., Even though the role of GLP-1 on neuroprotection is well-known and new clinical trials have been started for its repurposing in neuroprotection, the role of GLP-1 on reward systems and its potential clinical use for reward modulation still need further studies
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