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J Exp Med 2021;218:e20210446
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However, the most worrying are the long-term adverse effects that have been described, such as an increase in cardiovascular complications, the development of T2D, and different types of cancer, which is why its application in real life as an antiaging therapy continues to be controversial and requires further studies to define the stage in life in which it would be most useful, the optimal time of use, and ways of monitoring and preventing its adverse effects
In the context of hair biology, copper peptides have been proposed to act through several mechanisms, based primarily on in vitro and animal research: Stimulating hair follicle proliferation by promoting the activity of dermal papilla cells, which are critical regulators of the hair growth cycle observed in preclinical studies