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Mato JM, Martnez-Chantar ML, Lu SC

Last month (May 2025), Novo Nordisk and Septerna, a San Francisco, California-based bio/pharmaceutical company focused on GCPRs, formed an exclusive global collaboration and license agreement to discover, develop, and commercialize oral small-molecule medicines for treating obesity, Type 2 diabetes, and other cardiometabolic diseases, in a deal worth up to $2.2 billion ($200 million upfront and near-term funding and $2 billion in milestone payments)

This article intentionally focuses on the calculation method , not dosing recommendations, because the appropriate dose is a clinical decision not something a general calculator or article should attempt to guide

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