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AMPK activation depends on the upstream kinases liver kinase B1 (LKB1) and calcium/calmodulin-dependent protein kinase beta (CaMKK) [60], which phosphorylate AMPK under conditions such as oxidative stress, nutrient deprivation, or exercise, influencing metabolism and cell survival [61]

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By supporting detoxification pathways, glutathione promotes overall health and may reduce the risk of toxin-related diseases

Prevention of glutathione deficiency can slow down these processes

While these benefits are supported by subjective reports and clinical findings, further detailed studies could enhance the understanding of Maca's mechanisms and broader health impacts

Gallic acid attenuates dimethylnitrosamine-induced liver fibrosis by alteration of smad phosphoisoform signaling in rats