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These drugs are known as glucagon-like peptide-1 (GLP-1) receptor agonists, and they work by mimicking the naturally occurring GLP-1 hormone in the gut

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Additionally, recent studies suggest that alpha-cell-derived glucagon can serve as an additional, albeit less potent, ligand for the beta-cell GLP-1R, thereby expanding the role of alpha-cells beyond that of a counterregulatory cell type

Unfortunately, in vitro studies in neonatal cells and in vivo studies investigating the effects of glutamate on immune cell functions are lacking

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