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Few in vitro trials have explored this issue, 151 but no additional data are available to clarify it

Making frequent product changes is a common yet disastrous error

Specific dose adjustment recommendations for moderate renal or hepatic impairment have not been formally published

Due to encouraging signals from PD-related studies, and in the absence of direct DLB trial data, an international Delphi consensus has prioritized GLP-1RAs as candidates for repurposing in DLBs, underscoring the need for translational studies to confirm their therapeutic efficacy (164)

This effect on CKD progression persisted across all subgroups, although there was some heterogeneity of effect based on index date