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The ER and mitochondria form physical contacts through MAMs, which play a central role in calcium ion transport

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doi: 10.1097/ALN.0000000000004776

Specifically, regarding mitochondrial dysfunction, only the older adult cohort treated with GlyNAC significantly lowered 65% mitochondrial glucose oxidation (MGO), and upregulated 78% mitochondrial fatty-acid oxidation (MFO) towards levels not different from the young adult group