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A 1-year follow-up 1H-MR spectroscopic study

IGF-1 is produced predominantly in the liver in response to growth hormone stimulation, but it is also synthesized locally in many tissues where it exerts autocrine and paracrine effects

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Individuals who choose to take glutathione long term should follow recommended dosages and maintain regular medical guidance if needed

Compared to younger individuals, elderly patients typically exhibit reduced gut microbiota diversity, with a decline in beneficial bacterial groups such as Firmicutes and Actinobacteria and an increase in pathogenic groups such as Proteobacteria (Rondanelli et al., 2015