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Research on lean mass loss: For every 10 pounds lost, 2530% may come from lean mass, but this can be reduced with muscle-preserving strategies
This may include dose adjustment, slower titration, additional supportive measures, or transition to an alternative therapy if necessary
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In vitro models to study confinement-induced responses include micropatterned lines [151], 2D micropatterned substrates [85], uni-axial compression [152], polydimethylsiloxane [153,154,155,156]- or polyacrylamide [90]-based microchannel devices, microniches [157, 158], and natural hydrogels [148, 159]
Resistance training should begin in this phase if it has not already