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We know that macrocytosis is a very, very late stage of B12 deficiency and that severely deficient patients may not present with this sign, the administration of folic acid also masks macrocytosis by normalising the size of the blood cells

Though adverse effects havent been widely reported, side effects can vary based on individual health

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For example, in estrogen metabolism and regulation, the primary forms of estrogen are converted to various metabolites

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