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doi: 10.1101/gad.11.18.2295 70 XuY.GuB.HuangM.LiuH.XuT.XiaW.et al

Its expression appears lower in patients with NASH [110]

Nrf2 not only increases the enzyme levels of both the oxidative and non-oxidative arms, but it also facilitates the utilization of ribose 5-phosphate for the purine nucleotide synthesis (Mitsuishi et al., 2012), which appears to maintain the ribose 5-phosphate concentration at a low level and efficiently divert glucose flux into purine nucleotide synthesis through both arms of the pentose phosphate pathway

With proper lifestyle changes, results can offer long-term weight management

doi:10.1136/bmj-2023-076410

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