[4] The dominant pathway involves the enzyme butyryl-CoA:acetate CoA-transferase , utilized by key bacterial species including: - Often considered the champion butyrate producer, comprising up to 5% of total gut bacteria in healthy individuals Faecalibacterium prausnitzii and Eubacterium rectale - Together accounting for significant butyrate production Eubacterium hallii - Specialized in cross-feeding, converting lactate and acetate into butyrate Roseburia species - Efficient converters of lactate to butyrate Anaerostipes species The second pathway uses butyrate kinase , employed by various Coprococcus species and certain Clostridia
doi: 10.1089/ars.2016.6833
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