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& Yuan, Q
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6-AH is a metabolically stable antagonist to the HGF/c-Met system that works by preventing HGF dimerization and activation (Kawas et al., Statistical analysis Data were analyzed using GraphPad Prism (V
c-MET is overexpressed in 78% of HNSCC cases having phosphorylated at active sites Y1230, Y1234 and Y1235 [84, 85]
Int J Pharm 509:244254 Montazeri M, Pilehvar-Soltanahmadi Y, Mohaghegh M, Panahi A, Khodi S, Zarghami N et al (2017) Antiproliferative and apoptotic effect of dendrosomal curcumin nanoformulation in P53 mutant and wide-type cancer cell lines
Although old age is associated with increased utilization of APAP, mouse studies did not find increased hepatotoxicity after acute, chronic, and sub-acute APAP exposure in old mice [172]
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