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J Leukoc Biol 49:107115 Sandoval AJ, Riquelme JP, Carretta MD, Hancke JL, Hidalgo MA, Burgos RA (2007) Store-operated calcium entry mediates intracellular alkalinization, ERK1/2, and Akt/PKB phosphorylation in bovine neutrophils

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Furthermore, radioresistance and damage to normal brain tissue from radiotherapy, coupled with chemotherapy limitations including poor blood-brain barrier (BBB) penetration, drug resistance, and significant side effects, collectively reduce overall treatment efficacy [7]

Aspirin belongs to a class of drugs called salicylates, which works by inhibiting a chemical in the body that causes inflammation called prostaglandins (similar to ibuprofen)

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