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In some cases, vacuolar peptidases may cleave the glutamate and glycine of the original glutathione molecule, leaving the cysteinyl conjugate (cysteine-X) which may need further processing in Phase III reactions, such as incorporation into cell wall material

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Seizure frequency was assessed using patient-reported seizure diaries over the past year and categorized into the following groups: (a) 1 seizure per day to 2 per week, (b) 1 seizure per week to 1 per month, (c) less than 1 seizure per month to 1 every 6 months, and (d) 1 seizure per year

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Recent advances of data-independent acquisition mass spectrometry-based proteomics