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Interestingly, many studies have reported that various TNF-related molecules are present in preclinical models of AD

Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)

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De novo protein-altering mutations in BD probands led to noticeably earlier disease onset compared to non-carriers (Kataoka et al., 2016)

with different cytotoxicities (Utami et al., 2018)