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Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

A comparison of copper binding properties, copper exchange rate and redox potential between two similar naturally occurring copper-binding peptides GHK and DAHK shows that even though both bind copper in stoichiometry at a ratio of 1:1, the exchange rate of copper between DAHK peptides is very slow, while the exchange rate between GHK peptides is much faster

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Annals of Internal Medicine

Simultaneously, metformin activates the LKB1/AMPK signaling pathway, leading to the inhibition of aerobic glycolysis in cells, as well as the insulin-like growth factor-1(IGF-1) signaling pathway and mTOR pathway in EC cells