Its a concern that has sparked a lot of debate and research in the medical community
The rest is stored in organs like the liver, kidney, and brain
For example, patients with certain FTO or MC4R variants may benefit from a slower titration schedule or a lower-dose oral formulation initially, rather than jumping to injectable doses
Peeters B, Meersseman P, Vander Perre S, Wouters PJ, Vanmarcke D, Debaveye Y, et al
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Endotext 2021