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Initially Fab 3F52 was characterized in radioligand competition binding experiments using GLP-1R from various species in order to confirm the species specificity of mAb 3F52 shown previously by immunohistochemistry 25
LCMS/MS was performed on an UltiMate 3000 nano-flow system (Dionex/LC Packings) connected to an LTQ Orbitrap hybrid mass spectrometer Velos FTMS (Thermo Fisher Scientific) equipped with a nano-electrospray ion source
Res 14 , 13351342 (2019)
M.GladyshevV
These changes keep full GLP-1 receptor agonist activity while dramatically extending duration of action, creating an ideal treatment profile for chronic weight care
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